Fenasetin

Fenasetin

Fenasetin CAS:62-44-2

Fenasetin Chemical Properties

MF: C10H13NO2

MW: 179,22

Erime noktası: 133-136 ° C (aydınlık)

Kaynama noktası: 132 ° C / 4 mmHg

Yoğunluk: 1.1248 (kaba tahmin)

Fenasetin Specification:

% Â ‰ ¥ 99.0 tahlil

organik klorür% â ‰ ¤0.02

p-Fenetidinâ ¤ hafif kırmızıã € 4 #

Kolay karbon bileşiğiâ ‰ ¤4 # ã € 6 #

Kurutma kaybı% â ‰ ¤0.5

Erime noktası: 134-137oC

Ateşleme kalıntısı% â ‰ ¤0.1

Fenasetin Introduction:

Fenasetin is a non-opioid analgesic without anti-inflammatory properties, inhibits COX-3 activity.Target: COXFenasetin is a pain-relieving and fever-reducing drug,

 Fenasetin was withdrawn from the Canadian market in June 1973 due to concerns regarding nephropathy. the clinical and laboratory data were compatible with“phenacetin nephritis”as described in Europe and Australia and recently in the United States and Canada.

This report evaluates the findings in the 23 cases and cautions against the use of phenacetin, particularly in patients with impaired renal function [1]. Fenasetin has been linked to renal papillary necrosis in human beings [2, 3].

Fenasetin Application:

Ateş, baş ağrısı, nevralji vb. Tedavisinde kullanılan ateş düşürücü analjezik